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FAS Monoclonal Antibody

FAS Monoclonal Antibody

ArtNr	E-AB-70174-200
Hersteller	Elabscience
Menge	200 uL
Quantity options	120 uL 200 uL 60 uL
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Cholesterol & Lipid Metabolism Antibodies By Cell Type Carcinoma Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Immunohistochemistry Cardiovascular Research Ischemia & Reperfusion Injury Enzymes Fatty Acid Synthesis Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	IHC
Clon	10E5B10
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	ALPS 1A, ALPS1A, APO 1, Apo 1 antigen, APO 1 cell surface antigen, Apo-1 antigen, APO1, Apo1 antigen, APO1 cell surface antigen, Apoptosis antigen 1, Apoptosis mediating surface antigen FAS, Apoptosis-mediating surface antigen FAS, APT 1, APT1, CD 95, CD 95 antigen, CD95, CD95 antigen, Delta Fas, Delta Fas/APO 1/CD95, Delta Fas/APO1/CD95, Fas (TNF receptor superfamily, member 6), FAS 1, FAS 827dupA, Fas AMA, Fas, FAS Antigen, Fas cell surface death receptor, FAS1, FASLG receptor, FASTM, sFAS, Surface antigen APO1, TNF receptor superfamily, member 6, TNFRSF 6, TNFRSF6, TNR6, Tumor necrosis factor receptor superfamily member 6
Similar products	Fas, TNFRSF6, APT1, FAS1, Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, CD95, member 6, ALPS1A, FASTM, CD95 antigen, Fas AMA, APO1, ALPS 1A, APO 1, Apo 1 antigen, APO 1 cell surface antigen, Apo1 antigen, APO1 cell surface antigen, Apoptosis antigen 1, Apoptosis mediating surface antigen FAS, APT 1, CD 95, CD 95 antigen, Delta Fas, Delta Fas/APO 1/CD95, Delta Fas/APO1/CD95, FAS 1, FAS 827dupA, FAS Antigen, TNF receptor superfamily, TNFRSF 6, Fas (TNF receptor superfamily, TNR6
Versandbedingung	Gekühlt
Gefahren-Info	Comply with cargo safety certificate
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	FAS
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas	Cancer, Cell Biology, Immunology
Background	FAS, also named as CD95, APO-1, APT1, FAS1 and TNFRSF6, is a receptor for TNFSF6/FASLG. It is a cell surface receptor belonging to the TNF receptor superfamily, can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). This anti-Fas monoclonal antibody can be used to induce apoptosis in cell cultures through Fas by imitating the Fas-ligand.
Concentration	420 μg/mL
Buffer	PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Purification Method	Affinity purification
Recommended Dilution	IHC 1:200-1:800
Abbreviation	FAS
Clonality	Monoclonal
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse FAS
Category ID III	Monoclonal Antibodies

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