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AIFM1 Polyclonal Antibody

AIFM1 Polyclonal Antibody

ArtNr	E-AB-10123-120
Hersteller	Elabscience
Menge	120 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Kategorie	Neuroscience Neural Lineage Markers Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot ELISA Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies Microglia Markers Cytoskeleton Markers
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AIFM1, AIFM1, Apoptosis inducing factor 1, mitochondrial, Apoptosis inducing factor, Apoptosis inducing factor, mitochondrion associated, 1, Apoptosis-inducing factor 1, CMTX4, COWCK, COXPD6, Harlequin, Hq, mAIF, MGC111425, MGC5706, mitochondrial, Neuropathy, axonal motor-sensory, with deafness and mental retardation, neuropathy, axonal, motor-sensory with deafness and mental retardation (Cowchock syndrome), PDCD 8, PDCD8, Programmed cell death 8 (apoptosis inducing factor), Programmed cell death 8, Programmed cell death 8 isoform 1, Programmed cell death 8 isoform 2, Programmed cell death 8 isoform 3, Programmed cell death protein 8, Programmed cell death protein 8 mitochondrial, Programmed cell death protein 8 mitochondrial precursor, Programmed cell death protein 8 mitochondrial precursor, Striatal apoptosis inducing factor
Similar products	AIFM1, PDCD8, mitochondrial, 1, MGC111425, Apoptosis inducing factor, Harlequin, Hq, MGC5706, PDCD 8, Programmed cell death 8, Programmed cell death 8 isoform 1, Programmed cell death 8 isoform 2, Programmed cell death 8 isoform 3, Programmed cell death protein 8 mitochondrial, Programmed cell death protein 8 mitochondrial precursor, Striatal apoptosis inducing factor, Apoptosis-inducing factor 1, CMTX4, COWCK, COXPD6, Programmed cell death protein 8, mitochondrion associated, Apoptosis inducing factor 1, mAIF, Neuropathy, axonal motor-sensory, with deafness and mental retardation, neuropathy, axonal, motor-sensory with deafness and mental retardation (Cowchock syndrome), Programmed cell death 8 (apoptosis inducing factor)
Versandbedingung	Gekühlt
Gefahren-Info	Comply with cargo safety certificate
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	AIFM1
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	67kDa
Manufacturer - Research Areas	Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism
Background	This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.
Concentration	0.2 mg/mL
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000; IHC 1:25-1:100
Santa Cruz #	sc-9417, sc-9416, sc-5586
Abbreviation	AIFM1
Clonality	Polyclonal
Immunogen	Recombinant protein of human AIFM1
Category ID III	Polyclonal Antibodies

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