ARRB1 Polyclonal Antibody

ARRB1

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

IHC 1:50-1:200

ARRB1

Recombinant protein of human ARRB1