PIM1 Polyclonal Antibody

PIM1

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

IHC 1:50-1:200

PIM1

Recombinant protein of human PIM1