ArtNr |
E-AB-14210-200 |
Hersteller |
Elabscience
|
Menge |
200 uL |
Quantity options |
120 uL
20 uL
200 uL
60 uL
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC, ELISA |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus) |
Host |
Rabbit |
Isotype |
IgG |
Konjugat/Tag |
Unconjugated |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
DNA replication licensing factor MCM6, MCG40308, Mcm6, MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe), MCM6 minichromosome maintenance deficient 6, MCM6, Minichromosome maintenance complex component 6, Minichromosome maintenance deficient (mis5 S. pombe) 6, Minichromosome maintenance deficient 6 homolog, Minichromosome maintenance protein 6, Mis5, MIS5 homolog, p105MCM |
Similar products |
MCM6, DNA replication licensing factor MCM6, p105MCM, Mcm6, MCG40308, Mis5, MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe), MIS5 homolog, MCM6 minichromosome maintenance deficient 6, Minichromosome maintenance complex component 6, Minichromosome maintenance deficient (mis5 S. pombe) 6, Minichromosome maintenance deficient 6 homolog, Minichromosome maintenance protein 6 |
Versandbedingung |
Gekühlt |
Lieferbar |
|
Manufacturer - Category |
Primary Antibodies |
Shipping Temperature |
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Storage Conditions |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Calculated Molecular Weight |
93kDa |
Research Areas |
Cancer, Epigenetics and Nuclear Signaling |
Background |
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. |
Concentration |
0.8 mg/mL |
Buffer |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method |
Affinity purification |
Recommended Dilution |
WB 1:500-1:2000; IHC 1:100-1:300 |
Santa Cruz # |
sc-9843, sc-9845, sc-22781 |
Abbreviation |
MCM6 |
Clonality |
Polyclonal |
Immunogen |
Recombinant protein of human MCM6 |
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