Vergleich

MCM6 Polyclonal Antibody

ArtNr E-AB-14210-200
Hersteller Elabscience
Menge 200 uL
Quantity options 120 uL 20 uL 200 uL 60 uL
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias DNA replication licensing factor MCM6, MCG40308, Mcm6, MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe), MCM6 minichromosome maintenance deficient 6, MCM6, Minichromosome maintenance complex component 6, Minichromosome maintenance deficient (mis5 S. pombe) 6, Minichromosome maintenance deficient 6 homolog, Minichromosome maintenance protein 6, Mis5, MIS5 homolog, p105MCM
Similar products MCM6, DNA replication licensing factor MCM6, p105MCM, Mcm6, MCG40308, Mis5, MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe), MIS5 homolog, MCM6 minichromosome maintenance deficient 6, Minichromosome maintenance complex component 6, Minichromosome maintenance deficient (mis5 S. pombe) 6, Minichromosome maintenance deficient 6 homolog, Minichromosome maintenance protein 6
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Category
Primary Antibodies
Shipping Temperature
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
93kDa
Research Areas
Cancer, Epigenetics and Nuclear Signaling
Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
Concentration
0.8 mg/mL
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Recommended Dilution
WB 1:500-1:2000; IHC 1:100-1:300
Santa Cruz #
sc-9843, sc-9845, sc-22781
Abbreviation
MCM6
Clonality
Polyclonal
Immunogen
Recombinant protein of human MCM6

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 uL
Lieferbar: In stock
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