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CASP3 Monoclonal Antibody

CASP3 Monoclonal Antibody

ArtNr	E-AB-22209-60
Hersteller	Elabscience
Menge	60 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Cell Biology Cell Status Apoptosis Immunohistochemistry Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	IHC-P
Clon	4B8
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	https://www.sciencedirect.com/science/article/pii/S0753332220302663
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	A830040C14Rik, Apopain, CASP-3, CASP3, CASP3, Casp3a, Caspase 3, Caspase 3, apoptosis-related cysteine peptidase, Caspase 3, apoptosis-related cysteine protease, Caspase 3, apoptosis-related cysteine protease a, Caspase-3 subunit p12, CC3, CPP-32, CPP32, CPP32B, Cysteine protease CPP32, EC 3.4.22.56, LICE, mldy, OTTHUMP00000165052, OTTHUMP00000165053, OTTHUMP00000165054, PARP cleavage protease, Procaspase3, Protein Yama, SCA 1, SCA-1, SREBP cleavage activity 1, Yama
Similar products	CASP3, CPP32, Apopain, Cysteine protease CPP32, Protein Yama, SREBP cleavage activity 1, Caspase-3 subunit p12, CC3, LICE, CASP-3, CPP-32, SCA-1, Caspase 3, apoptosis-related cysteine protease, CPP32B, PARP cleavage protease, Yama, A830040C14Rik, mldy, SCA 1, OTTHUMP00000165054, Procaspase3, Casp3a, apoptosis-related cysteine peptidase, apoptosis-related cysteine protease a, EC 3.4.22.56, OTTHUMP00000165052, OTTHUMP00000165053
Versandbedingung	Gekühlt
Gefahren-Info	Comply with cargo safety certificate
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	CASP3
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Manufacturer - Research Areas	Cancer, Cell Biology, Metabolism, Neuroscience
Background	Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
Concentration	1 mg/mL
Buffer	PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification Method	Protein A purification
Recommended Dilution	IHC 1:100-200
Abbreviation	CASP3
Clonality	Monoclonal
Immunogen	Synthetic Peptide of Caspase-3
Category ID III	Monoclonal Antibodies

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