DKC1 Polyclonal Antibody

Store at -20C. Avoid freeze / thaw cycles.

43kDa

This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.

PBS with 0.02% sodium azide and 50% glycerol pH 7.4

WB1:500 - 1:2000 IHC1:50 - 1:200 IF1:50 - 1:200