ACVR2A Polyclonal Antibody

ACVR2A

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

58kDa

This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

IHC 1:100-1:200; IF 1:50-1:200

Polyclonal

Polyclonal Antibodies