(KO Validated) PRMT6 Polyclonal Antibody

PRMT6

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

42kDa

The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

IF 1:50-1:200

Polyclonal

Polyclonal Antibodies