ALAS1 Polyclonal Antibody

ALAS1

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Refer to figures

This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

IF 1:50-1:200

Polyclonal

Polyclonal Antibodies