PTP4A2 Polyclonal Antibody

PTP4A2

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

19kDa

The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

IHC 1:50-1:200; IF 1:50-1:200

Polyclonal

Polyclonal Antibodies