ITGAV Polyclonal Antibody

ITGAV

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

IHC 1:300-1:1000

Polyclonal

Polyclonal Antibodies