SNCA Polyclonal Antibody

ArtNr	E-AB-64580-60
Hersteller	Elabscience
Menge	60 uL
Quantity options	120 uL 200 uL 60 uL
Kategorie	Oncology Neuroscience Neuroinflammation Neural Mitochondrial Function Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Infectious Diseases Viral Infections Coronavirus (COVID-19) Antibodies By Cell Type Cell Biology Cell Status Adenocarcinoma Immunohistochemistry Western Blot Autophagy Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PD1, NACP, PARK1, PARK4, SNCA
Similar products	Alpha synuclein, SNCA, NACP, PARK1, Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, SYN, MGC110988, PARK4, isoform NACP140, Synuclein, Synuclein alpha, alphaSYN, MGC105443, MGC127560, MGC64356, Non A beta component of AD amyloid, Non A4 component of amyloid precursor, Non-A-beta component of alzheimers disease amyloid, precursor of, PARK 1, PARK 4, Parkinson disease familial 1, Snca synuclein, Non A4 component of amyloid, Non-A4 component of amyloid, OTTHUMP00000218549, OTTHUMP00000218551, OTTHUMP00000218552, OTTHUMP00000218553, OTTHUMP00000218554, Parkinson disease (autosomal dominant, Lewy body) 4, alpha (non A4 component of amyloid precursor), Synuclein alpha 140
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Category	Polyclonal Antibody
Shipping Temperature	Biological Ice Packs
Storage Conditions	-20°C for 12 months
Calculated Molecular Weight	11kDa/13kDa/14kDa
Observed Molecular Weight	14kDa
Manufacturer - Research Areas	Cancer, Neuroscience
Background	Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
Concentration	1 mg/mL
Buffer	PBS with 0.01% thiomersal, 50% glycerol, pH 7.3.
Purification Method	Affinity purification
Recommended Dilution	WB 1:500 - 1:2000 IHC 1:50 - 1:200
Clonality	Polyclonal
Immunogen	Recombinant fusion protein of human SNCA

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