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Recombinant Human GM-CSF/CSF2 Protein (His Tag, Cells)

ArtNr ELS-PKSH032502-10ug
Hersteller Elabscience
Menge 10 ug
Quantity options 10 ug 50 ug
Kategorie
Typ Proteins
Format Lyophilized Powder
Applikationen Cell Culture
Specific against Human (Homo sapiens)
Host HEK293 cells
Konjugat/Tag HIS
Purity > 95 % as determined by reducing SDS-PAGE.
Sequence Ala18-Glu144
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CSF, CSF2, Colony-Stimulating Factor, GM-CSF, GMCSF, Granulocyte-Macrophage Colony-Stimulating Factor, Molgramostin, Sargramostim
Similar products CSF2, GM-CSF, GMCSF, CSF, Molgramostin, Sargramostim, Colony-Stimulating Factor, Granulocyte-Macrophage Colony-Stimulating Factor
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Category
Recombinant Proteins / Cytokines
Manufacturer - Conjugate / Tag
C-His
Shipping Temperature
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Calculated Molecular Weight
15.5 kDa
Observed Molecular Weight
17-30 kDa
Research Areas
immunology
Background
Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells; B cells; macrophages; mast cells; endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors; GM-CSF is also a growth factor for erythroid; megakaryocyte and eosinophil progenitors. On mature hematopoietic; monocytes/ macrophages and eosinophils. GM-CSF has a functional role on non-hematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally; GM-CSF can also stimulate the proliferation of a number of tumor cell lines; including osteogenic sarcoma; carcinoma and adenocarcinoma cell lines.
Abbreviation
GM-CSF; CSF2
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution
Please refer to the printed manual for detailed information.
Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Activity
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 6-30 pg/ml.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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