ArtNr |
ELS-PKSH032741-10ug |
Hersteller |
Elabscience
|
Menge |
10 ug |
Quantity options |
10 ug
50 ug
|
Kategorie |
|
Typ |
Proteins |
Format |
Lyophilized Powder |
Applikationen |
Cell Culture |
Specific against |
Human (Homo sapiens) |
Host |
HEK293 cells |
Konjugat/Tag |
HIS |
Purity |
> 95 % as determined by reducing SDS-PAGE. |
Sequence |
Glu33-Arg255 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
CSF-1, CSF1, Lanimostim, M-CSF, MCSF, Macrophage Colony-Stimulating Factor 1, SCF-1 |
Similar products |
MCSF, M-CSF, CSF1, CSF-1, Lanimostim, Macrophage Colony-Stimulating Factor 1, SCF-1 |
Versandbedingung |
Gekühlt |
Lieferbar |
|
Manufacturer - Category |
Recombinant Proteins / Cytokines |
Manufacturer - Conjugate / Tag |
C-His |
Shipping Temperature |
This product is provided as lyophilized powder which is shipped with ice packs. |
Storage Conditions |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Calculated Molecular Weight |
26.2 kDa |
Observed Molecular Weight |
41 kDa |
Research Areas |
Cardiovascular, immunology |
Background |
Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. CSF-1 is required for normal male and female fertility and promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. it also plays a role in lipoprotein clearance. |
Abbreviation |
M-CSF; CSF1 |
Endotoxin |
< 0.01 EU per μg of the protein as determined by the LAL method. |
Reconstitution |
Please refer to the printed manual for detailed information. |
Formulation |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Activity |
Measured in a cell proliferation assay using M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 4.16 ng/ml. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.