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Recombinant Human M-CSF/CSF1 Protein (His Tag)

ArtNr ELS-PKSH032741-10ug
Hersteller Elabscience
Menge 10 ug
Quantity options 10 ug 50 ug
Kategorie
Typ Proteins
Format Lyophilized Powder
Applikationen Cell Culture
Specific against Human (Homo sapiens)
Host HEK293 cells
Konjugat/Tag HIS
Purity > 95 % as determined by reducing SDS-PAGE.
Sequence Glu33-Arg255
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CSF-1, CSF1, Lanimostim, M-CSF, MCSF, Macrophage Colony-Stimulating Factor 1, SCF-1
Similar products MCSF, M-CSF, CSF1, CSF-1, Lanimostim, Macrophage Colony-Stimulating Factor 1, SCF-1
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Category
Recombinant Proteins / Cytokines
Manufacturer - Conjugate / Tag
C-His
Shipping Temperature
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Calculated Molecular Weight
26.2 kDa
Observed Molecular Weight
41 kDa
Research Areas
Cardiovascular, immunology
Background
Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. CSF-1 is required for normal male and female fertility and promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. it also plays a role in lipoprotein clearance.
Abbreviation
M-CSF; CSF1
Endotoxin
< 0.01 EU per μg of the protein as determined by the LAL method.
Reconstitution
Please refer to the printed manual for detailed information.
Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Activity
Measured in a cell proliferation assay using M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 4.16 ng/ml.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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