ArtNr |
ELS-PKSH033172-50ug |
Hersteller |
Elabscience
|
Menge |
50 ug |
Quantity options |
10 ug
50 ug
|
Kategorie |
|
Typ |
Proteins |
Format |
Lyophilized Powder |
Specific against |
Human (Homo sapiens) |
Host |
E.coli |
Konjugat/Tag |
HIS |
Purity |
> 90 % as determined by reducing SDS-PAGE. |
Sequence |
Met 1-Tyr133 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
CASM, Cancer-Associated Sm-Like, LSM1, Small Nuclear Ribonuclear CaSm, U6 snRNA-Associated Sm-Like Protein LSm1 |
Similar products |
LSM1, CASM, U6 snRNA-Associated Sm-Like Protein LSm1, Cancer-Associated Sm-Like, Small Nuclear Ribonuclear CaSm |
Versandbedingung |
Gekühlt |
Lieferbar |
|
Manufacturer - Category |
Recombinant Proteins / Others |
Manufacturer - Conjugate / Tag |
C-His |
Shipping Temperature |
This product is provided as lyophilized powder which is shipped with ice packs. |
Storage Conditions |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Calculated Molecular Weight |
16.2 kDa |
Observed Molecular Weight |
19 kDa |
Research Areas |
Tags & Cell Markers, epigenetics and nuclear signal |
Background |
U6 snRNA-Associated Sm-Like Protein LSm1 (LSM1) belongs to the snRNP Sm proteins family. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which plays an important role in pre-mRNA splicing. LSM1 binds specifically to the 3-terminal U-tract of U6snRNA. LSM1 can interact with SLBP when histone mRNA is being rapidly degraded during the S phase. In addition, LSM1 is associated with cellular transformation and the progression of several malignancies including mesothelioma, lung cancer and breast cancer. |
Abbreviation |
LSM1 |
Endotoxin |
< 1.0 EU per μg of the protein as determined by the LAL method. |
Reconstitution |
Please refer to the printed manual for detailed information. |
Formulation |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Activity |
Not validated for activity |
Protein Construction |
Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm1 is produced by our E.coli expression system and the target gene encoding Met1-Tyr133 is expressed with a 6His tag at the C-terminus. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.