ArtNr |
ELS-PKSH033401-10ug |
Hersteller |
Elabscience
|
Menge |
10 ug |
Quantity options |
10 ug
50 ug
|
Kategorie |
|
Typ |
Proteins |
Format |
Lyophilized Powder |
Specific against |
Human (Homo sapiens) |
Host |
HEK293 cells |
Konjugat/Tag |
HIS, Fc |
Purity |
> 95 % as determined by reducing SDS-PAGE. |
Sequence |
Gln27-Ser220 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
B-lymphocyte activation marker BLAST-1, BCM1, BCM1 surface antigen, BLAST1, CD48, CD48 antigen, Leukocyte antigen MEM-102, SLAMF2, TCT.1, hCD48, mCD48 |
Similar products |
SLAMF2, CD48, BCM1, BLAST1, hCD48, mCD48, B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, CD48 antigen, Leukocyte antigen MEM-102, TCT.1 |
Versandbedingung |
Gekühlt |
Lieferbar |
|
Manufacturer - Category |
Recombinant Proteins / Immune Checkpoint Proteins |
Manufacturer - Conjugate / Tag |
C-Fc-His |
Shipping Temperature |
This product is provided as lyophilized powder which is shipped with ice packs. |
Storage Conditions |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Calculated Molecular Weight |
50.3 kDa |
Observed Molecular Weight |
71 kDa |
Research Areas |
immunology |
Background |
CD48 antigen; also known as B-lymphocyte activation marker BLAST-1; BCM1 surface antigen; Leukocyte antigen MEM-102; TCT.1; CD48; BCM1; and BLAST1; CD48 contains one Ig-like C2-type domain and one Ig-like V-type domain; but does not have a transmembrane domain; however; but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. CD48 may facilitate interaction between activated lymphocytes and be involved in regulating T-cell activation. CD48 plays a vital role as an environmental sensor for regulating progenitor cell numbers and inhibiting tumor development. It is suggested that the anti-CD48 mAb has the potential to become an effective therapeutic mAb against multiple myeloma. |
Abbreviation |
CD48 |
Endotoxin |
< 1.0 EU per μg of the protein as determined by the LAL method. |
Reconstitution |
Please refer to the printed manual for detailed information. |
Formulation |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Activity |
Not validated for activity |
Protein Construction |
Recombinant Human SLAM Family Member 2 is produced by our Mammalian expression system and the target gene encoding Gln27-Ser220 is expressed with a Fc; 6His tag at the C-terminus. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.