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Recombinant Human TrkB/NTRK2 Protein (His Tag)

ArtNr ELS-PKSH033579-10ug
Hersteller Elabscience
Menge 10 ug
Quantity options 10 ug 50 ug
Kategorie
Typ Proteins
Format Lyophilized Powder
Applikationen ELISA
Specific against Human (Homo sapiens)
Host HEK293 cells
Konjugat/Tag HIS
Purity > 95 % as determined by reducing SDS-PAGE.
Sequence Cys32-His430
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias BDNF/NT-3 Growth Factors Receptor, GP145-TrkB, NTRK2, Neurotrophic Tyrosine Kinase Receptor Type 2, TRKB, Trk-B, TrkB Tyrosine Kinase, Tropomyosin-Related Kinase B
Similar products NTRK2, Trk-B, GP145-TrkB, TRKB, Neurotrophic Tyrosine Kinase Receptor Type 2, BDNF/NT-3 Growth Factors Receptor, TrkB Tyrosine Kinase, Tropomyosin-Related Kinase B
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Category
Recombinant Proteins / Others
Manufacturer - Conjugate / Tag
C-His
Shipping Temperature
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
45.3 kDa
Observed Molecular Weight
60-105 kDa
Manufacturer - Research Areas
Neuroscience, Cancer, metabolism
Background
The TRK Family of Tyrosine Kinase Receptor consists of 3 members: TrkA, TrkB and TrkC. The three TRK family proteins have different ligand specificities. They connect to different neurotrophins, including NGF, BDNF, NT-3NT-4/5. TRKA binds NGF, TRKB binds BDNF and NT-3, TRKC binds NT-4/5. At the protein sequence level, human and rat TRKB have greater than 90% sequence identity and the proteins exbihit cross-species activity. TRKB is primarily expressed in the nervous system and it also expression in a wide variety of tissues with low levels.
Abbreviation
TrkB; NTRK2
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution
Please refer to the printed manual for detailed information.
Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Activity
Not validated for activity

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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