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Recombinant Human ASXL1 Protein (GST Tag)

ArtNr ELS-PKSH033781-50ug
Hersteller Elabscience
Menge 50 ug
Quantity options 10 ug 50 ug
Kategorie
Typ Proteins
Format Liquid
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag GST
Purity > 90 % as determined by reducing SDS-PAGE.
Sequence Lys1477-Arg1541
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias ASXL1, Additional sex combs-like protein 1, KIAA0978, Putative Polycomb group protein ASXL1
Similar products ASXL1, KIAA0978, Putative Polycomb group protein ASXL1, Additional sex combs-like protein 1
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Category
Recombinant Proteins / Others
Manufacturer - Conjugate / Tag
N-GST
Shipping Temperature
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
33.6 kDa
Observed Molecular Weight
38 kDa
Manufacturer - Research Areas
Signal Transduction, epigenetics and nuclear signal,
Background
Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). It acts as coactivator of RARA and RXRA through association with NCOA1. ASXL1 also acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 to respective promoters.
Abbreviation
ASXL1
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution
Not Applicable
Formulation
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Activity
Not validated for activity
Protein Construction
Recombinant Human ASXL1 is produced by our E.coli expression system and the target gene encoding Lys1477-Arg1541 is expressed with a GST tag at the N-terminus.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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