Vergleich

Recombinant Mouse Biglycan/BGN Protein (Fc Tag)

ArtNr ELS-PKSM040496-100ug
Hersteller Elabscience
Menge 100 ug
Quantity options 100 ug 50 ug
Kategorie
Typ Proteins
Format Lyophilized Powder
Specific against Mouse (Murine, Mus musculus)
Host HEK293 cells
Konjugat/Tag C-hFc
Purity > 85 % as determined by reducing SDS-PAGE.
Sequence Met1-Lys369
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias BG, DSPG1, PG-S1, PGI, SLRR1A
Similar products PGI, BG, DSPG1, PG-S1, SLRR1A
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Category
Recombinant Proteins / Others
Manufacturer - Conjugate / Tag
C-hFc
Shipping Temperature
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
66.5 kDa
Observed Molecular Weight
67 kDa
Background
Biglycan, also known as PG-S1 and BGN, is a a small leucine-rich repeat proteoglycan (SLRP). It can be detected in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Biglycan consists of a protein core containing leucine-rich repeat regions and two glycosaminoglycan (GAG) chains consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Non-glycanated forms of biglycan (no GAG chains) increase with age in human articular cartilage. Biglycan interacts with collagen, both via the core protein and GAG chains. Biglycan plays a role in the mineralisation of bone. Biglycan core protein binds to the growth factors BMP-4 and influences its bioactivity.
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution
Please refer to the printed manual for detailed information.
Formulation
Lyophilized from sterile PBS, pH 7.4
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Activity
Not validated for activity
Protein Construction
A DNA sequence encoding the mouse BGN (Met1-Lys369) was expressed with the Fc region of human IgG1 at the C-terminus.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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