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Recombinant Rat CD40/TNFRSF5 Protein (Fc Tag)

Recombinant Rat CD40/TNFRSF5 Protein (Fc Tag)

ArtNr	ELS-PKSR030349-50ug
Hersteller	Elabscience
Menge	50 ug
Quantity options	100 ug 50 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Aging & Neurological Disorders By Cell Type Hematology Lymphoma Peptides & Proteins Recombinant Proteins Neurodegeneration Markers
Typ	Proteins
Format	Lyophilized Powder
Specific against	Rat (Rattus norvegicus)
Host	HEK293 cells
Konjugat/Tag	C-hFc
Purity	> 95 % as determined by reducing SDS-PAGE.
Sequence	Met1-Arg193
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD40, Tnfrsf5
Similar products	CD40, Tnfrsf5
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Category	Recombinant Proteins / Immune Checkpoint Proteins
Manufacturer - Conjugate / Tag	C-hFc
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	46.2 kDa
Observed Molecular Weight	53 kDa
Background	CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Please refer to the printed manual for detailed information.
Formulation	Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Not validated for activity
Protein Construction	A DNA sequence encoding the rat CD40 (Q4QQW2) (Met1-Arg193) was expressed, fused with the Fc region of human IgG1 at the C-terminus.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

ELS-PKSR030349-50ug-datasheet.pdf

ELS-PKSR030349-50ug-safety-datasheet.pdf