MCL-1 Antibody

ArtNr	E10-20027
Hersteller	Enogene
Menge	100 ug/100 ul
Kategorie	Oncology Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies
Typ	Antibody
Applikationen	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	EAT, MCL1L, MCL1S
Similar products	MCL-1
Lieferbar
Manufacturer - Applications	WB, IHC, IF, ELISA. Not yet tested in other applications. Determining optimal working dilutions by titration test.
Manufacturer - Conjugate / Tag	This antibody is also available with the following conjugates: AF350, AF405L, AF405M, AF405S, AF488, AF514, AF532, AF546, AF555, AF568, AF594, AF610, AF635, AF647, AF680, AF700, AF750, AF790, APC, AP, Biotin, Cy3, Cy5.5, Cy5, Cy7, FITC, HRP, PE, Magnetic beads (1 um, 2.8 um, 3 um, 4.5 um, 5 um, 10 um, 15 um, 20 um, 30 um, or different size option) Please contact sales@hoelzel.de for pricing and availability.
Storage Conditions	Store at 4C, for long term storage, store at -20C
Molecular Weight	37kDa
Immunogen	Purified recombinant fragment of human MCL-1 expressed in E. Coli
Research Area	Autophagy antibody, Cancer, Cardiovascular, Cell Biology, Epigenetics and Nuclear Signaling, Developmental Biologys, Immunology, Drug Discovery Products, Metabolism, Neuroscience, Signal Transduction, Stem Cells
Background	Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.This monoclonal antibody detected a 37kd MCL1 in BCBL-1 cell lysate.
Recommended Dilutions	WB.1/500 - 1/2000, IHC.1/200 - 1/1000, IF.1/200 - 1/1000, ELISA. Propose dilution 1/10000.
Formulation Description	Purified antibody in PBS containing 0.03% sodium azide
CiteID	EN0013301

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E10-20027-datasheet.pdf

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Menge: 100 ug/100 ul

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Lieferung vsl. bis 23.10.2025

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