CHK1 Antibody

ArtNr	E10-20031
Hersteller	Enogene
Menge	100 ug/100 ul
Quantity options	100 ug/100 ul 100 ul 100 ul 100 ul 100 ul 100 ul 100 ul 50 ul
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Western Blot ELISA Primary Antibodies
Typ	Antibody
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens)
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CHEK1
Similar products	CHK1
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Manufacturer - Applications	WB, ELISA. Not yet tested in other applications. Determining optimal working dilutions by titration test.
Manufacturer - Conjugate / Tag	This antibody is also available with the following conjugates: AF350, AF405L, AF405M, AF405S, AF488, AF514, AF532, AF546, AF555, AF568, AF594, AF610, AF635, AF647, AF680, AF700, AF750, AF790, APC, AP, Biotin, Cy3, Cy5.5, Cy5, Cy7, FITC, HRP, PE, Magnetic beads (1 um, 2.8 um, 3 um, 4.5 um, 5 um, 10 um, 15 um, 20 um, 30 um, or different size option) Please contact sales@hoelzel.de for pricing and availability.
Storage Conditions	Store at 4C, for long term storage, store at -20C
Molecular Weight	56kDa
Immunogen	Purified recombinant fragment of CHK1 expressed in E. Coli.
Research Area	Autophagy antibody, Cancer, Cardiovascular, Cell Biology, Epigenetics and Nuclear Signaling, Developmental Biologys, Immunology, Drug Discovery Products, Metabolism, Neuroscience, Signal Transduction, Stem Cells
Background	CHK1, also known as CHEK1, it is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when phosphorylated on serine 216 by chk1 becomes bound by an adaptor protein in the cytoplasm. Therefore it is inhibited from removing the inhibiting phosphate from MPF (mitotic/maturation promoting factor) added by Wee1. Consequently, a cell is prevented from entering mitosis. Chk1 can also phosphorylate p53 at Ser20 in vitro.
Recommended Dilutions	WB.1/500 - 1/2000, ELISA. Propose dilution 1/10000.
Formulation Description	Purified antibody in PBS containing 0.03% sodium azide
CiteID	EN0013304

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E10-20031-datasheet.pdf

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Menge: 100 ug/100 ul

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Lieferung vsl. bis 23.10.2025

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