Caspase 10 Antibody

ArtNr	E18-0122-1
Hersteller	Enogene
Menge	50 ug/50 ul
Quantity options	100 ug/100 ul 100 ug/100 ul 50 ug/50 ul 100 ug/100 ul 100 ul 100 ul
Kategorie	Oncology Neuroscience Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Aging & Neurological Disorders Neural Signaling Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer Gastric Cancer Uterine, Ovarian & Cervical Cancer
Typ	Antibody
Applikationen	WB, IF, IHC, ICC
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ALPS2, Apoptotic protease Mch-4, CASP-10, CASP10, CASPA, caspase 10, apoptosis-related cysteine peptidase, caspase 10, apoptosis-related cysteine protease, Caspase-10, Caspase-10 subunit p12, Caspase-10 subunit p23/17, FADD-like ICE2, FAS-associated death
Lieferbar
Specificity	Caspase 10 antibody detects endogenous levels of total Caspase 10
Manufacturer - Applications	WB: 1:500~1:3000 IHC: 1:50~1:200 IF/ICC: 1:100~1:500
Manufacturer - Conjugate / Tag	This antibody is also available with the following conjugates: AF350, AF405L, AF405M, AF405S, AF488, AF514, AF532, AF546, AF555, AF568, AF594, AF610, AF635, AF647, AF680, AF700, AF750, AF790, APC, AP, Biotin, Cy3, Cy5.5, Cy5, Cy7, FITC, HRP, PE, Magnetic beads (1 um, 2.8 um, 3 um, 4.5 um, 5 um, 10 um, 15 um, 20 um, 30 um, or different size option) Please contact sales@hoelzel.de for pricing and availability.
Storage Conditions	Store at -20C/1 year
Molecular Weight	60kDa
Immunogen	A synthesized peptide derived from human Caspase 10
Purification	Affinity-chromatography
Background	Casp10 Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase- 3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-\|-AMC and Asp-Glu-Val-Asp-\|-AMC. Belongs to the peptidase C14A family. Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 23/17 kDa (p23/17) (depending on the splicing events) and a 12 kDa (p12) subunit. Self-associates. Interacts with FADD and CASP8. Found in a Fas signaling complex consisting of FAS, FADD, CASP8 and CASP10. 6 isoforms of the human protein are produced by alternative splicing.
Formulation Description	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 C.Stable for 12 months from date of receipt
CiteID	EN0035320

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Menge: 50 ug/50 ul

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