p300 Antibody

ArtNr	E18-0674-2
Hersteller	Enogene
Menge	100 ug/100 ul
Quantity options	100 ug/100 ul 100 ug/100 ul 50 ug/50 ul 100 ug/100 ul 50 ug/50 ul 100 ug/100 ul 100 ul 100 ul 100 ul
Kategorie	Oncology Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody
Applikationen	WB, IHC
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	E1A-associated protein p300, EC 2.3.1.48, EP300, P300 transcription coactivator homolog
Lieferbar
Specificity	p300 Antibody detects endogenous levels of p300
Manufacturer - Applications	WB 1:500-1:2000 IHC 1:50-1:200
Manufacturer - Conjugate / Tag	This antibody is also available with the following conjugates: AF350, AF405L, AF405M, AF405S, AF488, AF514, AF532, AF546, AF555, AF568, AF594, AF610, AF635, AF647, AF680, AF700, AF750, AF790, APC, AP, Biotin, Cy3, Cy5.5, Cy5, Cy7, FITC, HRP, PE, Magnetic beads (1 um, 2.8 um, 3 um, 4.5 um, 5 um, 10 um, 15 um, 20 um, 30 um, or different size option) Please contact sales@hoelzel.de for pricing and availability.
Storage Conditions	Store at -20C/1 year
Molecular Weight	264kDa
Immunogen	A synthesized peptide derived from human p300
Purification	Immunogen affinity purified
Background	p300 is a histone acetyltransferase and transcriptional co-activator that regulates transcription via chromatin remodeling. Acetylates all four core histones in nucleosomes. Related to CPB (CREB-binding protein), and like CPB can stimulate transcription through activation of CREB. Specifically inhibited by the adenovirus oncoprotein E1A. A co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. Methylated at R580 and R604 in the KIX domain by CARM1, which blocks association with CREB, inhibits CREB signaling and activates the apoptotic response. Also methylated at R2142 by CARM1, which impairs interaction with NCoA2.
Formulation Description	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 C.Stable for 12 months from date of receipt
CiteID	EN0036203

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Menge: 100 ug/100 ul

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Lieferung vsl. bis 23.10.2025

Express-Lieferung: 27 Tage sparen

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