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STAT3 Antibody

ArtNr E10-30122
Hersteller Enogene
Menge 100 ug/100 ul
Quantity options 100 ug/100 ul 100 ug/100 ul 100 ug/100 ul 100 ug 50 ug/50 ul 100 ug/100 ul 50 ug/50 ul 100 ug/100 ul 50 ug/50 ul 100 ug/100 ul 50 ug/50 ul 100 ug/100 ul 100 ug 200 ul 200 ul 200 ul 200 ul 100 ug/200 ul 200 ul 100 ul 100 ul 100 ug/100 ul 100 ul 100 ul 100 ul
Kategorie
Typ Antibody
Format Liquid
Applikationen WB, IF, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Monkey (Cynomolgus, Simian)
Host Mouse
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias APRF, HIES, FLJ20882, MGC16063, STAT3
Similar products STAT3
Lieferbar
Manufacturer - Applications
WB, IHC, IF, ELISA. Not yet tested in other applications.
Manufacturer - Conjugate / Tag
This antibody is also available with the following conjugates:
AF350, AF405L, AF405M, AF405S, AF488, AF514, AF532, AF546, AF555, AF568, AF594, AF610, AF635, AF647, AF680, AF700, AF750, AF790, APC, AP, Biotin, Cy3, Cy5.5, Cy5, Cy7, FITC, HRP, PE, Magnetic beads (1 um, 2.8 um, 3 um, 4.5 um, 5 um, 10 um, 15 um, 20 um, 30 um, or different size option)
Please contact sales@hoelzel.de for pricing and availability.
Storage Conditions
Store at 4C, for long term storage, store at -20C.
Molecular Weight
88kDa
Immunogen
Purified recombinant fragment of human STAT3 expressed in E. Coli.
Research Area
Autophagy antibody, Cancer, Cardiovascular, Cell Biology, Epigenetics and Nuclear Signaling, Developmental Biologys, Immunology, Drug Discovery Products, Metabolism, Neuroscience, Signal Transduction, Stem Cells
Background
The Stat3 transcription factor is an important signaling molecule for many cytokines and growth-factor receptors and is required for murine fetal development . Stat3 is constitutively activated in a number of human tumors and possesses oncogenic potential and anti-apoptotic activities. Stat3 is activated by phosphorylation at Tyr705, which induces dimerization, nuclear translocation and DNA binding. Transcriptional activation seems to be regulated by phosphorylation at Ser727 through the MAPK or mTOR pathways. Stat3 isoform expression appears to reflect biological function as the relative expression levels of Stat3alpha (86 kDa) and Stat3beta (79 kDa) depend on cell type, ligand exposure or cell maturation stage. It is notable that Stat3beta lacks the serine phosphorylation site within the carboxy-terminal transcriptional activation domain.Tissue specificity: Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Recommended Dilutions
WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF: 1/200 - 1/1000,
ELISA: Propose dilution 1/10000.
Formulation Description
Ascitic fluid containing 0.03% sodium azide.
CiteID
EN0013798

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/100 ul
Lieferbar: In stock
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