RUNX1 Antibody

ArtNr	E19-6785
Hersteller	Enogene
Menge	100 ug/100 ul
Quantity options	100 ug/100 ul 100 ug/100 ul 100 ug/100 ul 100 ug/200 ul 100 ul 100 ul 100 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Molecular Targets for Neuroscience Neural Signaling Neural Development Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Melanoma Sarcoma Immunohistochemistry Western Blot Cardiovascular Research Atherosclerosis Primary Antibodies
Typ	Antibody
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AML1, AML1-EVI-1, AMLCR1, CBFA2, EVI-1, PEBP2Ab,
Lieferbar
Specificity	RUNX1 Antibody detects endogenous levels of total RUNX1
Manufacturer - Applications	WB 1:500-1:2000 IHC 1:50-1:200
Manufacturer - Conjugate / Tag	This antibody is also available with the following conjugates: AF350, AF405L, AF405M, AF405S, AF488, AF514, AF532, AF546, AF555, AF568, AF594, AF610, AF635, AF647, AF680, AF700, AF750, AF790, APC, AP, Biotin, Cy3, Cy5.5, Cy5, Cy7, FITC, HRP, PE, Magnetic beads (1 um, 2.8 um, 3 um, 4.5 um, 5 um, 10 um, 15 um, 20 um, 30 um, or different size option) Please contact sales@hoelzel.de for pricing and availability.
Storage Conditions	Store at -20C/1 year
Molecular Weight	51kDa
Immunogen	A synthetic peptideof human RUNX1
Purification	Immunogen affinity purified
Background	AML1 (also known as Runx1, CBFA2, and PEBP2alphaB) is a member of the core binding factor (CBF) family of transcription factors (1, 2). It is required for normal development of all hematopoietic lineages (3-5). AML1 forms a heterodimeric DNA binding complex with its partner protein CBFbeta and regulates the expression of cellular genes by binding to promoter and enhancer elements. AML1 is commonly translocated in hematopoietic cancers: chromosomal translocations include t(8; 21) AML1-ETO, t(12; 21) TEL-AML, and t(8; 21) AML-M2 (6). Phosphorylation of AML1 on several potential serine and threonine sites, including Ser249, is thought to occur in an Erk-dependent manner (7, 8).
Formulation Description	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 C.Stable for 12 months from date of receipt
CiteID	EN0043062

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Menge: 100 ug/100 ul

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Lieferung vsl. bis 27.11.2025

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