STAT3 Antibody

ArtNr	E91192
Hersteller	Enogene
Menge	100 ul
Quantity options	100 ug/100 ul 100 ug/100 ul 100 ug/100 ul 100 ug 50 ug/50 ul 100 ug/100 ul 50 ug/50 ul 100 ug/100 ul 50 ug/50 ul 100 ug/100 ul 50 ug/50 ul 100 ug/100 ul 100 ug 200 ul 200 ul 200 ul 200 ul 100 ug/200 ul 200 ul 100 ul 100 ul 100 ug/100 ul 100 ul 100 ul 100 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Neural Transcription Factors Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Adenocarcinoma Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	STAT3, APRF, FLJ20882, HIES, MGC16063 ,
Lieferbar
Manufacturer - Conjugate / Tag	This antibody is also available with the following conjugates: AF350, AF405L, AF405M, AF405S, AF488, AF514, AF532, AF546, AF555, AF568, AF594, AF610, AF635, AF647, AF680, AF700, AF750, AF790, APC, AP, Biotin, Cy3, Cy5.5, Cy5, Cy7, FITC, HRP, PE, Magnetic beads (1 um, 2.8 um, 3 um, 4.5 um, 5 um, 10 um, 15 um, 20 um, 30 um, or different size option) Please contact sales@hoelzel.de for pricing and availability.
Storage Conditions	Store at -20C or -80oC. Avoid freeze / thaw cycles.
Molecular Weight	88kDa
Immunogen	Recombinant protein of human STAT3
Research Area	Autophagy antibody, Cancer, Cardiovascular, Cell Biology, Epigenetics and Nuclear Signaling, Developmental Biologys, Immunology, Drug Discovery Products, Metabolism, Neuroscience, Signal Transduction, Stem Cells
Background	The Stat3 transcription factor is an important signaling molecule for many cytokines and growth factor receptors (1) and is required for murine fetal development (2). Stat3 is constitutively activated in a number of human tumors (3, 4) and possesses oncogenic potential (5) and anti-apoptotic activities (3). Stat3 is activated by phosphorylation at Tyr705, which induces dimerization, nuclear translocation, and DNA binding (6, 7). Transcriptional activation seems to be regulated by phosphorylation at Ser727 through the MAPK or mTOR pathways (8, 9). Stat3 isoform expression appears to reflect biological function as the relative expression levels of Stat3alpha (86 kDa) and Stat3beta (79 kDa) depend on cell type, ligand exposure, or cell maturation stage (10). It is notable that Stat3beta lacks the serine phosphorylation site within the carboxy-terminal transcriptional activation domain (8).
Formulation Description	Rabbit IgG in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
CiteID	EN0126737

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E91192-datasheet.pdf

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Menge: 100 ul

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Lieferung vsl. bis 26.02.2026

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