FOXA2 Antibody

This antibody is also available with the following conjugates:
AF350, AF405L, AF405M, AF405S, AF488, AF514, AF532, AF546, AF555, AF568, AF594, AF610, AF635, AF647, AF680, AF700, AF750, AF790, APC, AP, Biotin, Cy3, Cy5.5, Cy5, Cy7, FITC, HRP, PE, Magnetic beads (1 um, 2.8 um, 3 um, 4.5 um, 5 um, 10 um, 15 um, 20 um, 30 um, or different size option)
Please contact sales@hoelzel.de for pricing and availability.

52kDa

Affinity purification

Forkhead box protein A2 (FoxA2, also known as hepatocyte nuclear factor 3beta or HNF3beta) is a transcription factor that plays an important role in hepatocyte function (1). FoxA2/HNF3beta is required for the activation of hepatic gluconeogenic gene expression during fasting (1). Together with the PGC-1beta coactivator, FoxA2/HNF3beta stimulates the expression of genes involved in fatty acid beta-oxidation and therefore increases fatty acid metabolism (2). FoxA2/HNF3beta, along with PGC-1beta, also activates the expression of microsomal triacylglycerol transfer protein (MTP) and promotes VLDL secretion (2). In addition to its roles in metabolic syndromes, FoxA2/HNF3beta is essential for development of the endoderm and midline structures in mouse embryos (3-5).

EN0134115