Vergleich

Human FGF-10 / KGF 2 Protein, His Tag Europäischer Partner

ArtNr FG0-H5145-1mg
Hersteller ACROBiosystems
Menge 200 ug x 5
Quantity options 100 ug 200 ug x 5
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag Unconjugated
Purity 95%
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias FGF-10,Fibroblast growth factor 10,Keratinocyte growth factor 2
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
21.2 kDa
Manufacturer - Format
Powder
Description
Human FGF-10 Protein, His Tag (FG0-H5145) is expressed from E. coli cells. It contains AA Gln 38 - Ser 208 (Accession # O15520-1).
Background
Fibroblast Growth Factor 10 (FGF 10) is an evolutionary conserved secreted growth factor mediating mostly mesenchymal to epithelial signaling. FGF 10 belongs to the FGF 7 subfamily and shares similar biochemical and amino acid sequences with its constituent members (FGF3, FGF 7 and FGF 22). As a paracrine FGF, FGF 10 elicits its biological responses by activating the fibroblast growth factor receptor 2b (FGF R 2b), is crucial for governing proximal distal outgrowth as well as patterning and acts upstream of the known apical ectodermal ridge (AER) marker FGF 8. FGF10 is also implicated in pancreatic cancer, and that overexpression of FGFR2b is associated with metastatic invasion.
Molecule
FGF-10
Exp Region
Gln 38 - Ser 208
Characteristics
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 21.2 kDa. The protein migrates as 27 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin
0.1 EU per μg
Buffer
20 mM MOPS, 200 mM NaCl, 100 mM Na2SO4, 1mM DTT, pH 7.0
Stability
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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