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Amyloid-Beta (1-38) (FL) ELISA Kit

Amyloid-Beta (1-38) (FL) ELISA Kit

ArtNr	27717
Hersteller	Fivephoton
Menge	1 kit, 96 T
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding By Cell Type Adenocarcinoma ELISA ELISA & Immunoassays ELISA Kits Immunoassay
Typ	Elisa-Kit
Specific against	Human (Homo sapiens)
Citations	Selkoe DJ. Normal and abnormal biology of the beta-amyloid precursor protein. Annu Rev Neurosci. 1994;17:489-517. Wang R, Sweeney D, Gandy SE, Sisodia SS. The profile of soluble amyloid beta protein in cultured cell media. Detection and quantification of amyloid beta protein and variants by immunoprecipitation-mass spectrometry. J Biol Chem. 1996 Dec 13;271(50):31894-902 Weggen S, Eriksen JL, Das P, Sagi SA, Wang R, Pietrzik CU, Findlay KA, Smith TE, Murphy MP, Bulter T, Kang DE, Marquez-Sterling N, Golde TE, Koo EH. A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity. Nature. 2001 Nov 8;414(6860):212-6.
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Gefahren-Info	Sodium Azide (0.1%)
Lieferbar
Manufacturer - Targets	APP
Storage Conditions	4°C
Poisonous Material	Sodium Azide (0.1%)
Background	Amyloid-beta (Abeta) is formed through amyloid precursor protein (APP) cleavage by certain secretases. Beta-secretase cleaves an extracellular portion of APP and frees a soluble portion. Gamma-secretase cleaves APP within the transmembrane domain, creating amyloid-beta (Abeta) isoforms with lengths between 36-43 amino acid residues. The prevailing isoforms of Amyloid-Beta are Abeta40 and Abeta42. Abeta40 is the most widespread amyloid-Beta (Abeta) isoform, while Abeta42 is more fibrillogenic and is the principal Abeta peptide associated with Alzheimer’s disease. Antibodies used in this ELISA kit are selective to Abeta38 , with insignificant cross-reactivity to Abeta33 .
Highlights	Complete 96T ELISA kit in sandwich format. Colorimetric detection at 450 nm. ELISA plate is coated with an affinity purified monoclonal antibody that recognizes amyloid-beta 1-38 (FL). The kit detects amyloid-beta 1-38 in EDTA-plasma, cerebrospinal fluids, serum, cell culture media or brain tissue extract. EIA buffer contains 1% BSA, 0.05% Tween 20 in PBS Incubation times: Samples with plate; overnight. Detection antibody: 1 hr Assay range: 9.38 - 600 pg/ml

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Menge: 1 kit, 96 T

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Lieferung vsl. bis 02.10.2025

Express-Lieferung: 6 Tage sparen

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