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Amyloid-Beta (1-38) (FL) ELISA Kit

Amyloid-Beta (1-38) (FL) ELISA Kit

Item no.	27717
Manufacturer	Fivephoton
Amount	1 kit, 96 T
Category	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding By Cell Type Adenocarcinoma ELISA ELISA & Immunoassays ELISA Kits Immunoassay
Type	Elisa-Kit
Specific against	Human (Homo sapiens)
Citations	Selkoe DJ. Normal and abnormal biology of the beta-amyloid precursor protein. Annu Rev Neurosci. 1994;17:489-517. Wang R, Sweeney D, Gandy SE, Sisodia SS. The profile of soluble amyloid beta protein in cultured cell media. Detection and quantification of amyloid beta protein and variants by immunoprecipitation-mass spectrometry. J Biol Chem. 1996 Dec 13;271(50):31894-902 Weggen S, Eriksen JL, Das P, Sagi SA, Wang R, Pietrzik CU, Findlay KA, Smith TE, Murphy MP, Bulter T, Kang DE, Marquez-Sterling N, Golde TE, Koo EH. A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity. Nature. 2001 Nov 8;414(6860):212-6.
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Hazard information	Sodium Azide (0.1%)
Available
Manufacturer - Targets	APP
Storage Conditions	4°C
Poisonous Material	Sodium Azide (0.1%)
Background	Amyloid-beta (Abeta) is formed through amyloid precursor protein (APP) cleavage by certain secretases. Beta-secretase cleaves an extracellular portion of APP and frees a soluble portion. Gamma-secretase cleaves APP within the transmembrane domain, creating amyloid-beta (Abeta) isoforms with lengths between 36-43 amino acid residues. The prevailing isoforms of Amyloid-Beta are Abeta40 and Abeta42. Abeta40 is the most widespread amyloid-Beta (Abeta) isoform, while Abeta42 is more fibrillogenic and is the principal Abeta peptide associated with Alzheimer’s disease. Antibodies used in this ELISA kit are selective to Abeta38 , with insignificant cross-reactivity to Abeta33 .
Highlights	Complete 96T ELISA kit in sandwich format. Colorimetric detection at 450 nm. ELISA plate is coated with an affinity purified monoclonal antibody that recognizes amyloid-beta 1-38 (FL). The kit detects amyloid-beta 1-38 in EDTA-plasma, cerebrospinal fluids, serum, cell culture media or brain tissue extract. EIA buffer contains 1% BSA, 0.05% Tween 20 in PBS Incubation times: Samples with plate; overnight. Detection antibody: 1 hr Assay range: 9.38 - 600 pg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 kit, 96 T

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Delivery expected until 10/2/2025

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