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Sumo1 (SUMO 1, SUMO-1, Small Ubiquitin-Related Modifier 1, human specificity) ELISA Kit

Sumo1 (SUMO 1, SUMO-1, Small Ubiquitin-Related Modifier 1, human specificity) ELISA Kit

ArtNr	hSUMO1ELISA-biotin
Hersteller	Fivephoton
Menge	1 kit, 96 T
Kategorie	Cell Biology Cell Status ELISA Autophagy ELISA & Immunoassays ELISA Kits Immunoassay
Typ	Elisa-Kit
Specific against	Human (Homo sapiens)
Citations	Shen Z, Pardington-Purtymun PE, Comeaux JC, Moyzis RK, Chen DJ (January 1997). "UBL1, a human ubiquitin-like protein associating with human RAD51/RAD52 proteins". Genomics 36 (2): 271-9. doi:10.1006/geno.1996.0462. PMID 8812453. Okura T, Gong L, Kamitani T, Wada T, Okura I, Wei CF, Chang HM, Yeh ET (Dec 1996). "Protection against Fas/APO-1- and tumor necrosis factor-mediated cell death by a novel protein, sentrin". J Immunol 157 (10): 4277-81. PMID 8906799. Entrez Gene: SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)". Pauws E, Stanier P (December 2007). "FGF signalling and SUMO modification: new players in the aetiology of cleft lip and/or palate". Trends Genet. 23 (12): 631-40. doi:10.1016/j.tig.2007.09.002. PMID 17981355. Dixon MJ, Marazita ML, Beaty TH, Murray JC (2011). "Cleft lip and palate: understanding genetic and environmental influences". Nature Reviews Genetics (12) 167-178. Tatham, Michael H; Kim Suhkmann, Yu Bin, Jaffray Ellis, Song Jing, Zheng Jian, Rodriguez Manuel S, Hay Ronald T, Chen Yuan (August 2003). "Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation". Biochemistry (United States) 42 (33): 9959-69. doi:10.1021/bi0345283. ISSN 0006-2960. PMID 12924945.
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Lieferbar
Storage Conditions	4°C
Background	SUMO 1 functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. SUMO1 is involved in a variety of cellular processes, including nuclear transport, transcriptional regulation, apoptosis, and protein stability. SUMO1 becomes functionally active when the last four amino acids of the carboxy-terminus are cleaved. SUMO 1 is also associated with SERCA2A, the sarco/endoplasmic reticulum Ca2+ ATPase that regulates intracellular calcium levels. SUMO 1 activates and stabilizes SERCA2A by binding to lysine resides 480 and 585. This ELISA kit detects free SUMO1 and conjugated SUMO1.
Highlights	Fully pre-configured ELISA kit in sandwich assay format. Dynamic Assay Range: 150pg/ml - 40ng/ml. Sensitivity: 128pg/ml. Standard peptide concentration: 48ng/ml Rapid and simple ELISA Protocol: Requires one 60 min incubation period at 37C. Samples are mixed with biotinylated detection antibody and streptavidin-HRP prior to addition to the plate. Available in 48T and 96T formats.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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hSUMO1ELISA-biotin-safety-datasheet.pdf