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Kallikrein-6 ELISA Kit (KLK6; Part No. KLK6-ELISA, 96T)

Kallikrein-6 ELISA Kit (KLK6; Part No. KLK6-ELISA, 96T)

ArtNr	KLK6-ELISA
Hersteller	Fivephoton
Menge	1 kit, 96 T
Kategorie	Oncology Food Safety Allergenes Neuroscience Neural Lineage Markers ELISA ELISA & Immunoassays ELISA Kits Immunoassay By Organ Colorectal Cancer Testicular & Prostate Cancer Gastric Cancer Uterine, Ovarian & Cervical Cancer
Typ	Elisa-Kit
Specific against	Human (Homo sapiens)
Citations	Ashby EL, Kehoe PG, Love S. Kallikrein-related peptidase 6 in Alzheimer’s disease and vascular dementia. Brain Research 1363: 1-10, 2010. Diamandis EP, Yousef GM, Luo LY, Magklara A, Obiezu CV. The new human kallikrein gene family: implications in carcinogenesis. Trends in endocrinology and metabolism TEM 11: 54-60, 2000. Magklara A, Mellati AA, Wasney GA, Little SP, Sotiropoulou G, Becker GW, Diamandis EP. Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors. Biochemical and Biophysical Research Communications 307: 948-955, 2003. Menendez-Gonzalez M, Castro-Santos P, Suarez A, Calatayud MT, Perez-Pinera P, Martinez M, Ribacoba R, Gutierrez C. Value of measuring plasmatic levels of neurosin in the diagnosis of Alzheimer’s disease. Journal of Alzheimers disease JAD 14: 59-67, 2008. Ogawa K, Yamada T, Tsujioka Y, Taguchi J, Takahashi M, Tsuboi Y, Fujino Y, Nakajima M, Yamamoto T, Akatsu H, Mitsui S, Yamaguchi N. Localization of a novel type trypsin-like serine protease, neurosin, in brain tissues of Alzheimer’s disease and Parkinson's disease. Psychiatry and Clinical Neurosciences 54: 419-426, 2000. Okui A, Kominami K, Uemura H, Mitsui S, Yamaguchi N. Characterization of a brain-related serine protease, neurosin (human kaillikrein 6), in human cerebrospinal fluid. NeuroReport 12: 1345-1350, 2001. Shan SJC, Scorilas A, Katsaros D, Diamandis EP. Transcriptional upregulation of human tissue kallikrein 6 in ovarian cancer: clinical and mechanistic aspects. British Journal of Cancer 96: 362-372, 2007.
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Gefahren-Info	Sodium Azide (0.1%)
Lieferbar
Manufacturer - Targets	KLK6
Storage Conditions	4°C
Poisonous Material	Sodium Azide (0.1%)
Background	Kallikrein-6 (KLK-6) is a secretory protein with serine protease activity that is regulated by steroid hormones and implicated in carcinogenesis and amyloid precursor protein cleavage. Kallikrein-6 also cleaves myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Furthermore, Kallikrein-6 cleaves alpha-synuclein and prevents its polymerization. Kallikrein-6 is detected with gray matter neurons and colocalizes with pathological inclusions such as Lewy bodies and glial cytoplasmic inclusions.
Highlights	Fully pre-configured sandwich ELISA format providing convenience, high selectivity and sensitivity Affinity purified polyclonal capture antibody coated on plate. Separate HRP-conjugated detection antibody. Rapid colorimetric detection. 1 hr total incubation at 37C; 2 hr incubation at RT Suitable for cell and tissue lysates, cell culture medium, serum and plasma

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 1 kit, 96 T

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Lieferung vsl. bis 02.10.2025

Express-Lieferung: 7 Tage sparen

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