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CPG-Ferrocene (HPT1001-0010)

CPG-Ferrocene (HPT1001-0010)

ArtNr	HPT1001-0010
Hersteller	Fivephoton
Menge	100 mg
Kategorie	Reagents & Chemicals Molecules
Typ	Molecules
Specific against	other
Citations	Anne A, Bouchardon A, Moiroux J. 2003. 3'-Ferrocene-labeled oligonucleotide chains end-tethered to gold electrode surfaces: novel model systems for exploring flexibility of short DNA using cyclic voltammetry. J Am Chem Soc 125: 1112-3. Anne A, Demaille C. 2006. Dynamics of electron transport by elastic bending of short DNA duplexes. Experimental study and quantitative modeling of the cyclic voltammetric behavior of 3'-ferrocenyl DNA end-grafted on gold. J Am Chem Soc 128: 542-57. Jenkins DM, Chami B, Kreuzer M, Presting G, Alvarez AM, Liaw BY. 2006. Hybridization probe for femtomolar quantification of selected nucleic acid sequences on a disposable electrode. Anal Chem 78: 2314-8. Munoz-Serrano L, Guadalupe AR, Vega-Bermudez E. 2005. Morphological studies of oligodeoxyribonucleotides probes covalently immobilized at polystyrene modified surfaces. J Biotechnol 118: 233-45. Radi AE, Acero Sanchez JL, Baldrich E, O'Sullivan CK. 2006. Reagentless, reusable, ultrasensitive electrochemical molecular beacon aptasensor. J Am Chem Soc 128: 117-24. Wu ZS, Jiang JH, Shen GL, Yu RQ. 2007. Highly sensitive DNA detection and point mutation identification: an electrochemical approach based on the combined use of ligase and reverse molecular beacon. Hum Mutat 28: 630-7.
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Lieferbar
Storage Conditions	-20°C, desiccate
Description	Overview: 3’-Ferrocene CPG is a reagent used in oligonucleotide synthesis. Ferrocene CPG is used to attach a Ferrocene molecule at the 3’-end of oligonucleotides. A Ferrocene linked oligonucleotide provides high sensitivity detection with electrochemical techniques such as impedance analysis. Specifications: Chemical Name: 1-Dimethoxytrityloxy-3-N-carboxy-Ferrocene- propyl-2-O-succinoyl-long chain alkylamino-CPG. Purity: >98% purity Appearance: Light yellow solid Storage: 4oC, desiccate. Ships at ambient temperature
Background	CPG-Ferrocene is a 3’-Ferrocene labeled solid support used for labeling oligos from the 3’-end during oligonucleotide synthesis. Compared with Ferrocene NHS Ester conjugation of primary amino-linked oligonucleotides, CPG-Ferrocene provides direct labeling of Ferrocene moieties with the benefit of substantially higher purity and convenience of purification. Labeled ferrocene oligonucleotides are detected by voltammetry. Coupling: This support should be used in a manner identical to a normal protected nucleoside support since it contains the DMT group. Deprotection: Deprotect using the protocol required by the nucleobases.
Highlights	3’-Ferrocene CPG is a reagent used in oligonucleotide synthesis. Ferrocene CPG is used to attach a Ferrocene molecule at the 3’-end of oligonucleotides. A Ferrocene linked oligonucleotide provides high sensitivity detection with electrochemical techniques such as impedance analysis.

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HPT1001-0010-safety-datasheet.pdf