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Human GCGR/Glucagon receptor Protein-VLP (GCR-HM00V)

Human GCGR/Glucagon receptor Protein-VLP (GCR-HM00V)

ArtNr	GCR-HM00V-100UG
Hersteller	KactusBio
Menge	100 ug
Kategorie	Metabolism Diabetes Glucose Homeostasis
Format	Liquid
Specific against	Human (Homo sapiens)
Host	HEK293
Purity	> 95% as determined by HPLC
Dry ice	Yes
Sequence	Met1-Phe477
Alias	Glucagon receptor,GL-R,GCGR,Glucagon R
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	GCGR
Shipping Temperature	Shipped with dry ice.
Storage Conditions	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight	The target protein has a predicted MW of 56 kDa.
Description	Recombinant Human GCGR/Glucagon receptor Protein-VLP is expressed from HEK293.It contains Met1-Phe477 (It may have cross reaction with anti-His antibody).
Background	The pancreatic hormone glucagon activates the glucagon receptor (GCGR), a class B seven-transmembrane G protein-coupled receptor that couples to the stimulatory heterotrimeric G protein and provokes PKA-dependent signaling cascades vital to hepatic glucose metabolism and islet insulin secretion. The GCGR expressed at the plasma membrane is constitutively ubiquitinated and upon agonist-activation, internalized GCGRs are deubiquitinated at early endosomes and recycled via Rab4-containing vesicles.
Endotoxin	Less than 1 EU per μg by the LAL method.
Formulation	Supplied as 0.22μm filtered solution in PBS, 150mM L-Arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Biotinylated	no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

GCR-HM00V-100UG-datasheet.pdf

GCR-HM00V-100UG-safety-datasheet.pdf