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Biotinylated Human GCGR/Glucagon receptor Protein-Nanodisc (GCR-HM10NB)

Biotinylated Human GCGR/Glucagon receptor Protein-Nanodisc (GCR-HM10NB)

ArtNr	GCR-HM10NB-100UG
Hersteller	KactusBio
Menge	100 ug
Kategorie	Metabolism Diabetes Glucose Homeostasis
Format	Liquid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	HIS
Dry ice	Yes
Sequence	Met1-Phe477
Alias	Glucagon receptor,GL-R,GCGR,Glucagon R
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	GCGR/Glucagon receptor
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	Shipped with dry ice.
Storage Conditions	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight	The protein has a predicted MW of 66.9 kDa.
Description	Recombinant Biotinylated Human GCGR/Glucagon receptor Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Phe477.
Background	The pancreatic hormone glucagon activates the glucagon receptor (GCGR), a class B seven-transmembrane G protein-coupled receptor that couples to the stimulatory heterotrimeric G protein and provokes PKA-dependent signaling cascades vital to hepatic glucose metabolism and islet insulin secretion. The GCGR expressed at the plasma membrane is constitutively ubiquitinated and upon agonist-activation, internalized GCGRs are deubiquitinated at early endosomes and recycled via Rab4-containing vesicles.
Endotoxin	Less than 1 EU per μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Biotinylated	yes

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

GCR-HM10NB-100UG-datasheet.pdf

GCR-HM10NB-100UG-safety-datasheet.pdf