AP2M1 Antibody, pAb, Rabbit

USA

GenScript Rabbit Anti-AP2M1 Polyclonal Antibody detects endogenous levels of human AP2M1 protein. Sequence homology predicts that it will also react with mouse and rat AP2M1 proteins.

AP2M1 is a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunit family. AP2 is a heterotetramer composed of two large adaptins (either alpha-type subunit AP2A1 or AP2A2 paired with beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1). These component link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. GenScript, Rabbit Anti-AP2M1 Polyclonal Antibody, is developed in rabbit hosts using a synthetic peptide (KLH-coupled) from N-terminal of human AP2M1 protein (Swiss Prot: Q96CW1).

Immunoaffinity chromatography

50 kD

Small volumes of antibody will occasionally become trapped in the seal of the product vial during shipment and storage. Before use, briefly centrifuge the vial to dislodge any liquid in the container's cap.