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Parkin Antibody, pAb, Rabbit

Parkin Antibody, pAb, Rabbit

ArtNr	A01250-40
Hersteller	GenScript
Menge	40 ug
Kategorie	Oncology Neuroscience Neuroinflammation Neural Mitochondrial Function Neural Signaling Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Autophagy Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer
Typ	Antibody Polyclonal
Applikationen	WB, FC, IHC, ELISA, other
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), other
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	A01250-Parkin_Antibody_pAb_Rabbit,Rabbit Anti-Parkin pAb,
Similar products	Parkin
Lieferbar
Specificity	Human, mouse, and rat. This product has not yet been tested with other species.
Manufacturer - Isotype	Rabbit IgG
Country of Origin	USA
Storage Conditions	The antibody is stable in lyophilized form if stored at -20C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8C. For long term storage, aliquot and store at -20C or below. Avoid repeated freezing and thawing cycles.
Manufacturer - Specificity	GenScript, Parkin Antibody, pAb, Rabbit, detects endogenous levels of human, mouse and rat parkin protein.
Concentration	0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Description	Parkin, also known as PARKIN2, is a novel protein in Ubl conjugation pathway. Parkin functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include CCNE1, SYT11, GPR37, and STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP and SEPT5. Parkin may play a more general role in the ubiquitin proteasomal pathway by participating in the removal and/or detoxification of abnormally folded or damaged protein. The protein may protect neurons against alpha synuclein toxicity, proteasomal dysfunction, GPR37 accumulation, and kainate-induced excitotoxicity. Defects in PARK2 are a cause of Parkinson disease (PD). GenScript, Parkin Antibody, pAb, Rabbit, is developed in rabbit using a KLH-coupled synthetic peptide within residues 300-350 of human parkin protein (Swiss Prot: O60260).
Immunogen	KLH-coupled synthetic peptide within residues 300-350 of human parkin protein (Swiss Prot: O60260)
Purification Method	Immunoaffinity chromatography
Reconstitution	Reconstitute the lyophilized powder with deionized water (or equivalent) to an final concentration of 0.5 mg/ml.
Observed Band Size	51 kD
Predicted Band Size	51 kD

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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A01250-40-datasheet.pdf

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Menge: 40 ug

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Lieferung vsl. bis 13.11.2025