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Parkin Antibody, pAb, Rabbit

Parkin Antibody, pAb, Rabbit

Item no.	A01250-40
Manufacturer	GenScript
Amount	40 ug
Category	Oncology Neuroscience Neuroinflammation Neural Mitochondrial Function Neural Signaling Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Autophagy Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer
Type	Antibody Polyclonal
Applications	WB, FC, IHC, ELISA, other
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), other
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	A01250-Parkin_Antibody_pAb_Rabbit,Rabbit Anti-Parkin pAb,
Similar products	Parkin
Available
Specificity	Human, mouse, and rat. This product has not yet been tested with other species.
Manufacturer - Isotype	Rabbit IgG
Country of Origin	USA
Storage Conditions	The antibody is stable in lyophilized form if stored at -20C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8C. For long term storage, aliquot and store at -20C or below. Avoid repeated freezing and thawing cycles.
Manufacturer - Specificity	GenScript, Parkin Antibody, pAb, Rabbit, detects endogenous levels of human, mouse and rat parkin protein.
Concentration	0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Description	Parkin, also known as PARKIN2, is a novel protein in Ubl conjugation pathway. Parkin functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include CCNE1, SYT11, GPR37, and STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP and SEPT5. Parkin may play a more general role in the ubiquitin proteasomal pathway by participating in the removal and/or detoxification of abnormally folded or damaged protein. The protein may protect neurons against alpha synuclein toxicity, proteasomal dysfunction, GPR37 accumulation, and kainate-induced excitotoxicity. Defects in PARK2 are a cause of Parkinson disease (PD). GenScript, Parkin Antibody, pAb, Rabbit, is developed in rabbit using a KLH-coupled synthetic peptide within residues 300-350 of human parkin protein (Swiss Prot: O60260).
Immunogen	KLH-coupled synthetic peptide within residues 300-350 of human parkin protein (Swiss Prot: O60260)
Purification Method	Immunoaffinity chromatography
Reconstitution	Reconstitute the lyophilized powder with deionized water (or equivalent) to an final concentration of 0.5 mg/ml.
Observed Band Size	51 kD
Predicted Band Size	51 kD

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 40 ug

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Delivery expected until 11/13/2025

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