NCAM Antibody, pAb, Rabbit

USA

GenScript Rabbit Anti-NCAM Polyclonal Antibody detects endogenous levels of rat and mouse NCAM. It is predicted to react with human NCAM according to sequence homology.

NCAM (neural cell adhesion molecule, CD56) is an adhesion glycoprotein. It contains five extracellular immunoglobulin-like domains followed by two fibronectin type III repeats. Alternative splicing gives rise to different cytoplasmic domains. NCAM is involved in neuronal attachment, neurite extension, and cell-cell interactions through homo and heterophilic interactions. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of NCAM. It is expressed on most neuroectodermal derived cell lines, tissues, and neoplasm. GenScript, Rabbit Anti-NCAM Polyclonal Antibody, is developed in rabbit using a KLH-coupled synthetic peptide within cytoplasmic residues 780-830 of human NCAM (Swiss Prot: P13591).

Immunoaffinity chromatography

Small volumes of antibody will occasionally become entrapped in the seal of the product vial during shipment and storage. Before use, briefly centrifuge the vial to dislodge any liquid in the container's cap.