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SNAI 1/2 Antibody, pAb, Rabbit Europäischer Partner

ArtNr A01641-40
Hersteller GenScript
Menge 40 ug
Kategorie
Typ Antibody Polyclonal
Applikationen WB, other
Specific against Human (Homo sapiens), other
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias A01641-SNAI2_Antibody_pAb_Rabbit,SNAIL Antibody, pAb, Rabbit, SNAI2 Antibody, pAb, Rabbit
Similar products SNAI
Lieferbar
Specificity Human. Reactivity to other species is not tested yet.
Country of Origin
USA
Storage Conditions
The antibody is stable in lyophilized form if stored at -20C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8C. For long term storage, aliquot and store at -20C or below. Avoid repeated freezing and thawing cycles.
Manufacturer - Specificity
GenScript, SNAI 1/2 Antibody, pAb, Rabbit, detects endogenous levels of human SNAI 1/2. Predicted to react with mouse and rat SNAI2 according to sequence homology. Positive Control: MCF-7, HEK293
Concentration
0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
Description
SNAl protein family is a transcriptional repressor which contains SNAl1 and SNAI2. SNAl protein binds to the E-cadherin promoter region to repress transcription during development. The binding of SNAI protein to integrin promoter sequences represses integrin expression and results in reduced cell adhesion. The tumor suppressor protein p53 induces SNAL expression in gamma-irradiated cells. Deletion mutations in the corresponding SNAI gene are associated with the pigmentation disorders Waardenburg Syndrome and Piebaldism. GenScript, SNAI 1/2 Antibody, pAb, Rabbit, is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human SNAl1 (Swiss Prot: O95863) and human SNAI2 (Swiss Prot: O43623).
Immunogen
KLH-coupled synthetic peptide from C-terminal of human SNAl1 (Swiss Prot: O95863) and human SNAI2 (Swiss Prot: O43623)
Purification Method
Immunoaffinity chromatography
Reconstitution
Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 40 ug
Lieferbar: In stock
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