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Glucocorticoid Receptor Antibody, pAb, Rabbit

Glucocorticoid Receptor Antibody, pAb, Rabbit

ArtNr	A01656-40
Hersteller	GenScript
Menge	40 ug
Kategorie	Oncology Antibodies By Cell Type Carcinoma Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, other
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), other
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	A01656-Glucocorticoid_Receptor_Antibody_pAb_Rabbit,Glucocorticoid Receptor Antibody, pAb, Rabbit,
Similar products	Glucocorticoid
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Specificity	Human and mouse. Reactivity to other species has not been tested yet.
Country of Origin	USA
Storage Conditions	The antibody is stable in lyophilized form if stored at -20C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8C. For long term storage, aliquot and store at -20C or below. Avoid repeated freezing and thawing cycles.
Manufacturer - Specificity	GenScript, Glucocorticoid Receptor Antibody, pAb, Rabbit, detects endogenous levels of human and mouse Glucocorticoid Receptor. Predicted to react with rat Glucocorticoid Receptor according to sequence homology. Positive Control: U251, MCF-7 and mouse liver
Concentration	0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Description	The glucocorticoid receptor (GR) can be activated by binding glucocorticoid (GC) at its C-terminal ligand-binding domain. Activation of glucocorticoid receptor can then dimerize and translocate to the nucleus and recruit co-activator proteins such as GRIP1 and SRC1, to bind GC response elements (GRE) and to activate transcription. Its localization within a cell appears to be dynamic, with nucleocytoplasmic shuttling of both ligand-bound GR and ‘resting’ GR in hormone-free cells. GenScript, Glucocorticoid Receptor Antibody, pAb, Rabbit, is developed in rabbit using a KLH-coupled synthetic peptide within residues 220-270 of human Glucocorticoid Receptor (Swiss Prot: P04150).
Immunogen	KLH-coupled synthetic peptide within residues 220-270 of Glucocorticoid Receptor (Swiss Prot: P04150)
Purification Method	Immunoaffinity chromatography
Reconstitution	Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Observed Band Size	85 kD, 80 kD
Predicted Band Size	86 kD

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Menge: 40 ug

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