Comparison

Glucocorticoid Receptor Antibody, pAb, Rabbit European Partner

Item no. A01656-40
Manufacturer GenScript
Amount 40 ug
Category
Type Antibody Polyclonal
Applications WB, other
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), other
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias A01656-Glucocorticoid_Receptor_Antibody_pAb_Rabbit,Glucocorticoid Receptor Antibody, pAb, Rabbit,
Similar products Glucocorticoid
Available
Specificity Human and mouse. Reactivity to other species has not been tested yet.
Country of Origin
USA
Storage Conditions
The antibody is stable in lyophilized form if stored at -20C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8C. For long term storage, aliquot and store at -20C or below. Avoid repeated freezing and thawing cycles.
Manufacturer - Specificity
GenScript, Glucocorticoid Receptor Antibody, pAb, Rabbit, detects endogenous levels of human and mouse Glucocorticoid Receptor. Predicted to react with rat Glucocorticoid Receptor according to sequence homology. Positive Control: U251, MCF-7 and mouse liver
Concentration
0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Description
The glucocorticoid receptor (GR) can be activated by binding glucocorticoid (GC) at its C-terminal ligand-binding domain. Activation of glucocorticoid receptor can then dimerize and translocate to the nucleus and recruit co-activator proteins such as GRIP1 and SRC1, to bind GC response elements (GRE) and to activate transcription. Its localization within a cell appears to be dynamic, with nucleocytoplasmic shuttling of both ligand-bound GR and ‘resting’ GR in hormone-free cells. GenScript, Glucocorticoid Receptor Antibody, pAb, Rabbit, is developed in rabbit using a KLH-coupled synthetic peptide within residues 220-270 of human Glucocorticoid Receptor (Swiss Prot: P04150).
Immunogen
KLH-coupled synthetic peptide within residues 220-270 of Glucocorticoid Receptor (Swiss Prot: P04150)
Purification Method
Immunoaffinity chromatography
Reconstitution
Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Observed Band Size
85 kD, 80 kD
Predicted Band Size
86 kD

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 40 ug
Available: In stock
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