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Fibronectin CS1 Peptide

Fibronectin CS1 Peptide

ArtNr	RP10838-5
Hersteller	GenScript
Menge	5 mg
Quantity options	1 mg 5 mg
Kategorie	Oncology Neuroscience Protein Aggregation, Clearance & Misfolding Neural Adhesion Molecules By Cell Type Hematology Myeloma Melanoma Peptides & Proteins Cell Biology Cell Movement Cell Adhesion Cell Stainings ECM Peptides
Typ	Peptides
Specific against	other
Purity	> 95%
Sequence	EILDVPST ; {GLU}{ILE}{LEU}{ASP}{VAL}{PRO}{SER}{THR}
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	peptide/RP10838-Fibronectin_Connecting_Segment_1_Fibronectin_CS1_EILDVPST, The connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. CS1 peptide of fibronectin, which lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastasis models. The use of Fibronectin CS1 Peptide might offer a promising therapeutic approach for combating and preventing cancer metastasis. </td></tr><tr><th>Solubility</th><td colspan="7"> The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents. </td></tr><tr><th>Purity</th><td colspan="7"> > 95% </td></tr><tr><th>Storage</th><td colspan="7"> Before use, store the peptide in the DRY form at 0-5C. For best and most repeatable results, rehydrate the peptide immediately before use. Do not re-freeze any unused portions. </td></tr><tr><th>Notes</th><td colspan="7"> This peptide is part of the fibronectin receptor which is identical to the integrin receptor of alpha4 beta1. It completely inhibits lymphocyte adhesion to CS1 and partially inhibits adhesion to intact fibronectin. The 38,000 Da fragment and has no effect on lymphocyte adhesion to an 80,000 Da fragment containing the RCDS adhesion null.</td></tr>
Similar products	Fibronectin
Lieferbar
Country of Origin	USA
Storage Conditions	Before use, store the peptide in the DRY form at 0-5C. For best and most repeatable results, rehydrate the peptide immediately before use. Do not re-freeze any unused portions.
Description	The connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. CS1 peptide of fibronectin, which lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastasis models. The use of Fibronectin CS1 Peptide might offer a promising therapeutic approach for combating and preventing cancer metastasis.
Solubility	The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
Notes	This peptide is part of the fibronectin receptor which is identical to the integrin receptor of alpha4 beta1. It completely inhibits lymphocyte adhesion to CS1 and partially inhibits adhesion to intact fibronectin. The 38, 000 Da fragment and has no effect on lymphocyte adhesion to an 80, 000 Da fragment containing the RCDS adhesion null.

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