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PACAP (6-27), human, ovine, rat

PACAP (6-27), human, ovine, rat

ArtNr	RP10337-0.5
Hersteller	GenScript
Menge	0.5 mg
Kategorie	Neuroscience Molecular Targets for Neuroscience Peptides & Proteins Peptides
Typ	Peptides
Specific against	Rat (Rattus norvegicus)
Purity	> 95%
Sequence	FTDSYSRYRKQMAVKKYLAAVL-NH2 ; {PHE}{THR}{ASP}{SER}{TYR}{SER}{ARG}{TYR}{ARG}{LYS}{GLN}{MET}{ALA}{VAL}{LYS}{LYS}{TYR}{LEU}{ALA}{ALA}{VAL}{LEU}-NH2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	peptide/RP10337-PACAP_6-27, PACAP (6-27), PACAP-27 inhibitor, is a specific inhibitor of PACAP-27 stimulated adenylate cyclase. It allows a clear functional discrimination between PACAP-27 and PACAP-38 receptors. PACAP-(6-27) diminished, in a dose-dependent manner, the increase in adrenal CA secretion induced by PACAP-27. The results also indicate that the CA response to either PACAP-27 or VIP was selectively inhibited by PACAP-(6-27) but not by VIP-(10-28). It is concluded that PAC1 receptor is primarily involved in the CA secretion induced by both PACAP-27 and VIP in the canine adrenal medulla in vivo.</td></tr><tr><th>Solubility</th><td colspan="7"> Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. </td></tr><tr><th>Purity</th><td colspan="7"> > 95% </td></tr><tr><th>Storage</th><td colspan="7"> Store at -20C. </td></tr><tr><th>Notes</th><td colspan="7"> For PACAP receptor studies. Inhibits PACAP27-stimulated but not PACAP38-stimulated adenylate cyclase activity</td></tr>
Similar products	PACAP
Lieferbar
Country of Origin	USA
Storage Conditions	Store at -20C.
Description	PACAP (6-27), PACAP-27 inhibitor, is a specific inhibitor of PACAP-27 stimulated adenylate cyclase. It allows a clear functional discrimination between PACAP-27 and PACAP-38 receptors. PACAP-(6-27) diminished, in a dose-dependent manner, the increase in adrenal CA secretion induced by PACAP-27. The results also indicate that the CA response to either PACAP-27 or VIP was selectively inhibited by PACAP-(6-27) but not by VIP-(10-28). It is concluded that PAC1 receptor is primarily involved in the CA secretion induced by both PACAP-27 and VIP in the canine adrenal medulla in vivo.
Solubility	Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
C-Terminal	NH2
Notes	For PACAP receptor studies. Inhibits PACAP27-stimulated but not PACAP38-stimulated adenylate cyclase activity

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Menge: 0.5 mg

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Lieferung vsl. bis 08.01.2026

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