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Comparison

PACAP (6-27), human, ovine, rat European Partner

Item no. RP10337-0.5
Manufacturer GenScript
Amount 0.5 mg
Category
Type Peptides
Specific against Rat (Rattus norvegicus)
Purity > 95%
Sequence FTDSYSRYRKQMAVKKYLAAVL-NH2 ; {PHE}{THR}{ASP}{SER}{TYR}{SER}{ARG}{TYR}{ARG}{LYS}{GLN}{MET}{ALA}{VAL}{LYS}{LYS}{TYR}{LEU}{ALA}{ALA}{VAL}{LEU}-NH2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias peptide/RP10337-PACAP_6-27, PACAP (6-27), PACAP-27 inhibitor, is a specific inhibitor of PACAP-27 stimulated adenylate cyclase. It allows a clear functional discrimination between PACAP-27 and PACAP-38 receptors. PACAP-(6-27) diminished, in a dose-dependent manner, the increase in adrenal CA secretion induced by PACAP-27. The results also indicate that the CA response to either PACAP-27 or VIP was selectively inhibited by PACAP-(6-27) but not by VIP-(10-28). It is concluded that PAC1 receptor is primarily involved in the CA secretion induced by both PACAP-27 and VIP in the canine adrenal medulla in vivo.</td></tr><tr><th>Solubility</th><td colspan="7"> Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. </td></tr><tr><th>Purity</th><td colspan="7"> > 95% </td></tr><tr><th>Storage</th><td colspan="7"> Store at -20C. </td></tr><tr><th>Notes</th><td colspan="7"> For PACAP receptor studies. Inhibits PACAP27-stimulated but not PACAP38-stimulated adenylate cyclase activity</td></tr>
Similar products PACAP
Available
Country of Origin
USA
Storage Conditions
Store at -20C.
Description
PACAP (6-27), PACAP-27 inhibitor, is a specific inhibitor of PACAP-27 stimulated adenylate cyclase. It allows a clear functional discrimination between PACAP-27 and PACAP-38 receptors. PACAP-(6-27) diminished, in a dose-dependent manner, the increase in adrenal CA secretion induced by PACAP-27. The results also indicate that the CA response to either PACAP-27 or VIP was selectively inhibited by PACAP-(6-27) but not by VIP-(10-28). It is concluded that PAC1 receptor is primarily involved in the CA secretion induced by both PACAP-27 and VIP in the canine adrenal medulla in vivo.
Solubility
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
C-Terminal
NH2
Notes
For PACAP receptor studies. Inhibits PACAP27-stimulated but not PACAP38-stimulated adenylate cyclase activity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5 mg
Available: In stock
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