Hersteller |
GenScript
|
Kategorie |
|
Typ |
Proteins |
Specific against |
Human |
Format |
Sterile Filtered White lyophilized (freeze-dried) powder. |
Menge |
1 mg |
ArtNr |
Z02731-1 |
Targets |
NFKB1, CD269 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Description |
BCMA, a member of the TNF receptor superfamily, binds to BAFF and APRIL. BCMA is expressed on mature B-cells and other B-cell lines and plays an important role in B cell development, function and regulation. BCMA also has the capability to activate NF-kappaB and JNK. The human BCMA gene codes for a 184 amino acid type I transmembrane protein, which contains a 54 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 107 amino acid extracellular domain. |
Endotoxin Level |
Less than 0.2EU/ug of rHuBCMA as determined by LAL method. |
Formulation |
Lyophilized from a 0.2µ, m filtered concentrated, solution in 30% acetonitrile, 0.1% TFA. |
M.W. |
Approximately 5.3 KDa, a single non-glycosylated polypeptide chain containing 50 amino acids. |
Product Line |
Cytokine, Chemokines & Growth Factors |
Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °, C. Further dilutions should be made in appropriate buffered solutions. |
Storage |
This lyophilized preparation is stable at 2-8 C, but should be kept at -20 C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 C to -70 C. Avoid repeated freeze/thaw cycles. |
Usage |
This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. |
Manufacturers Category |
Proteins |
Manufacturers Product Line |
Cytokines |
Product Origin |
USA |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.