RANTES/CCL5, Human

ArtNr	Z02832-1
Hersteller	GenScript
Menge	1 mg
Quantity options	1 mg 20 ug
Kategorie	Neuroscience Neuroinflammation Peptides & Proteins Recombinant Proteins Cell Biology Cell Movement Cell Migration & Invasion
Typ	Proteins
Format	Sterile Filtered White lyophilized (freeze-dried) powder.
Specific against	Human (Homo sapiens)
Purity	>98% by SDS-PAGE and HPLC analyses.
Sequence	SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	protein/Z02832-RANTES_CCL5_Human, CCL5 or RANTES (acronym for Regulated upon Activation, Normal T cell Expressed and presumably Secreted), was initially discovered by subtractive hybridization as a transcript expressed in T cells but not B cells. Eosinophilchemotactic activities released by thrombinstimulated human platelets have also been purified and found to be identical to RANTES. Besides T cells and platelets, RANTES has been reported to be produced by renal tubular epithelium, synovial fibroblasts and selected tumor cells.</td></tr><tr><th>M.W.</th><td colspan="7"> 7.8 kDa, a single non-glycosylated polypeptide chain containing 68 amino acids.</td></tr><tr><th>Purity</th><td colspan="7"> >98% by SDS-PAGE and HPLC analyses.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> Less than 0.2EU/ug of rHuRANTES/ CCL5 as determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human monocytes is less than 30 ng/ml, corresponding to a specific activity of &
Similar products	RANTES/
Versandbedingung	Gekühlt
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Specificity	Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human monocytes is less than 30 ng/ml, corresponding to a specific activity of ＞, 3.3 x 104 IU/mg.
Manufacturer - Category	Proteins
Country of Origin	USA
Shipping Temperature	4°C
Storage Conditions	-80°C
Molecular Weight	7.8 kDa, a single non-glycosylated polypeptide chain containing 68 amino acids.
Product Line	Chemokines
Manufacturer - Specificity	Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human monocytes is less than 30 ng/ml, corresponding to a specific activity of ＞, 3.3 x 104 IU/mg.
Description	CCL5 or RANTES (acronym for Regulated upon Activation, Normal T cell Expressed and presumably Secreted), was initially discovered by subtractive hybridization as a transcript expressed in T cells but not B cells. Eosinophilchemotactic activities released by thrombinstimulated human platelets have also been purified and found to be identical to RANTES. Besides T cells and platelets, RANTES has been reported to be produced by renal tubular epithelium, synovial fibroblasts and selected tumor cells.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °, C. Further dilutions should be made in appropriate buffered solutions.
Formulation	Lyophilized from a 0.2µ, m filtered concentrated solution in 20mM PB, pH 7.4, 100mM NaCl.
Endotoxin Level	Less than 0.2EU/ug of rHuRANTES/ CCL5 as determined by LAL method.
Usage	This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

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Menge: 1 mg

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Lieferung vsl. bis 28.08.2025