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MCP-3/CCL7, Human

MCP-3/CCL7, Human

ArtNr	Z02833-1
Hersteller	GenScript
Menge	1 mg (2x500 ug)
Quantity options	1 mg (2x500 ug) 10 ug
Kategorie	Oncology Food Safety Histamines Neuroscience Neuroinflammation Aging & Neurological Disorders By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Movement Cell Status Senescence Cell Migration & Invasion Astrocytoma By Organ Bladder Cancer Bone Cancer
Typ	Proteins
Format	Sterile Filtered White lyophilized (freeze-dried) powder.
Specific against	Human (Homo sapiens)
Purity	>97% by SDS-PAGE and HPLC analyses.
Sequence	QPVGINTSTT CCYRFINKKI PKQRLESYRR TTSSHCPREA VIFKTKLDKEICADPTQKWV QDFMKHLDKK TQTPKL
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	protein/Z02833-MCP-3_CCL7_Human, MCP2 and CCL7 are two monocyte chemotactic proteins produced by human MG63 osteosarcoma cells. Both MCP2 and CCL7 are members of the CC family of chemokines and share 62% and 71% amino acid sequence identity, respectively, with MCP1. CCL7 also shares 58% amino acid identity with MCP2.Similarly to other CC chemokines, all three MCP proteins are monocyte chemoattractants. In addition, the three MCPs can chemoattract activated NK cells as well as CD4+ and CD8+ T lymphocytes. All three cytokines have also been shown to attract eosinophils and induce histamine secretion from basophils.</td></tr><tr><th>M.W.</th><td colspan="7"> 9.0 kDa, a single, non-glycosylated polypeptide chain containing 76 amino acids.</td></tr><tr><th>Purity</th><td colspan="7"> >97% by SDS-PAGE and HPLC analyses.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> Less than 0.2EU/ug of rHuMCP-3/CCL7 as determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human monocytes is less than 80 ng/ml, corresponding to a specific activity of &
Similar products	MCP-3/CCL7
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Specificity	Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human monocytes is less than 80 ng/ml, corresponding to a specific activity of ＞, 1.3 x 104 IU/mg.
Country of Origin	USA
Storage Conditions	This lyophilized preparation is stable for several weeks at 2-8 C, but should be kept at -20 C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 C to -70 C. Avoid repeated freeze/thaw cycles.
Molecular Weight	9.0 kDa, a single, non-glycosylated polypeptide chain containing 76 amino acids.
Product Line	Cytokine, Chemokines & Growth Factors
Manufacturer - Specificity	Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human monocytes is less than 80 ng/ml, corresponding to a specific activity of ＞, 1.3 x 104 IU/mg.
Description	MCP2 and CCL7 are two monocyte chemotactic proteins produced by human MG63 osteosarcoma cells. Both MCP2 and CCL7 are members of the CC family of chemokines and share 62% and 71% amino acid sequence identity, respectively, with MCP1. CCL7 also shares 58% amino acid identity with MCP2.Similarly to other CC chemokines, all three MCP proteins are monocyte chemoattractants. In addition, the three MCPs can chemoattract activated NK cells as well as CD4+ and CD8+ T lymphocytes. All three cytokines have also been shown to attract eosinophils and induce histamine secretion from basophils.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20 °, C. Further dilutions should be made in appropriate buffered solutions.
Formulation	Lyophilized from a 0.2µ, m filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.
Endotoxin Level	Less than 0.2EU/ug of rHuMCP-3/CCL7 as determined by LAL method.
Usage	This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

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Z02833-1.pdf

Z02833-1-datasheet.pdf

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Menge: 1 mg (2x500 ug)

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Lieferung vsl. bis 24.07.2025

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